), lets just review what Wakefield claimed about the MMR vaccine back in 2019. 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But only ongoing clinical trials will show whether vaccinated individuals recognise SARS-CoV-2 variants differently, and whether mutations decrease vaccine protection in some vaccinated individuals. Deze pagina is voor het laatst bewerkt op 23 feb 2023 om 10:56. The present extremely critical situation forces me to spread this emergency call. [1] In 2018 he was elected president of the Society of International Economic Law (SIEL). Vanden Bossche is bij het publiek bekend vanwege zijn kritiek op het coronabeleid van overheden. #COVID19 #openthedebate, Geert Vanden Bossche (@GVDBossche) March 7, 2021. Also, as I said at the time, while it is possible that the B. pertussis bacteria is developing resistance to the vaccine through natural selection, the evidence that it is doing so struck me as weak and preliminary, just as the evidence claiming that SARS-CoV-2 is evolving to be resistant to current vaccines strikes me as weak and preliminary. He has a long list of companies and organizations he's worked with on vaccine discovery and preclinical research, including GSK, Novartis, Solvay Biologicals, and Bill & Melinda Gates Foundation. Up to this point, at its core and leaving aside minor variations, Dr. Vanden Bossches argument about COVID-19 vaccines and COVID-19 is pretty close to exactly the same argument that Wakefield fallaciously made about MMR and measles. He does apparently have some history working on vaccines. Dr. Vanden Bossche has publicized his letter on Twitter: In this open letter I am appealing to the @WHO and all stakeholders involved, no matter their conviction, to immediately declare such action as THE SINGLE MOST IMPORTANT PUBLIC HEALTH EMERGENCY OF INTERNATIONAL CONCERN. A certain friend of the blog has written about this (at least twice), as has Skeptical Raptor. Het gaat ook om een therapeutisch vaccin. His LinkedIn profile lists several impressive positions, including Head of the Vaccine Development Office for the German Centre for Infection Research (for seven months, August 2017-February 2018); Chief Innovation & Scientific Officer for Univac, where he claimed to be an inventor of a new vaccine technology based on natural killer (NK) cells (2014-2016); and the managing director of VARECO, claiming to be a consultant about vaccine development (2012-present). Omdat het coronavirus zal blijven rondwaren, zullen volgens hem de specifieke antistoffen steeds worden opgeroepen zodra het lichaam opnieuw met het virus wordt geconfronteerd. Reality aside, invoking the innate immune system provides two rhetorical benefits. Dat laatste standpunt wordt ook door een klein deel van de wetenschappelijke experts gehuldigd. He reminds me of another doctor who spread misinformation about COVID-19 vaccination based on an unbending principle of immunology to justify his concerns, without any clinical or epidemiological evidence to support it. It protects us from a multitude of pathogens, thereby preventing these pathogens from causing disease. The ongoing phase 3 trial of an adenovirus-vectored spike-based vaccine (Johnson & Johnson, NCT04505722) in South Africa, where the 501Y.V2 (B.1.351) strain with the Glu484Lys substitution is rapidly replacing pre-existing variants,11 might provide an opportunity to examine this question. Racing against the clock, I am completing my scientfic [sic] manuscript, the publication of which is, unfortunately, likely to come too late given the ever increasing threat from rapidly spreading, highly infectious variants. Je krijgt daardoor minder besmettingen en daardoor ook minder mutaties. Were in a race with the new variants, Sara Del Valle, a computational epidemiologist at the Los Alamos National Laboratory in New Mexico explained in a March 2021 feature in the scientific journal Nature. However, Dr. Vanden Bossches claims to have worked with the Gates Foundation, GAVI, and other vaccine-related enterprises does seem to be legitimate, which makes me wonder: Has he gone crank or is he a grifter? As I like to say, if you ever write anything that channels Andrew Wakefield, you really should reconsider your life choices. De Belgische wetenschapper Geert Vanden Bossche heeft het internet veroverd met zijn waarschuwing voor een wereldwijde ramp: de massale coronavaccinaties zouden een virusvariant kunnen creren die tegen de vaccins bestand is waardoor veel doden zouden vallen. Fact-checkers noemt Vanden Bossche marionetten van een georkestreerde smaadcampagne die zich als leek willen mengen in zulk complex gegeven als virologie. Wij staken ons licht op bij verschillende vakgenoten en hun oordeel over zijn stelling is eensluidend: Technische nonsens. Massavaccinatie middenin een pandemie, (zorgt) voor druk op virusstammen (om te muteren, veranderen naar een nieuwe vorm dus, red. Zie het als een kopieermachine, legt immunoloog Hans-Willem Snoeck (Columbia University, New York)op zijn beurt uit. Er zijn overigens niet veel mutaties nodig voor een bacterie om resistent te worden tegen een antibioticum. De statisten wilden eerder het herstel van het ancien rgime, onder meer van de staten- en standenorganisaties en de oude vrijheden van de Nederlandse gewesten. Training is achieved by regular exposure to a myriad of environmental agents, including pathogens. and to induce herd immunity (which is exactly the opposite of what current Covid-19 vaccines do as those increasingly turn vaccine recipients into asymptomatic carriers who are shedding virus). Maar bij corona is het nog niet aangetoond. Its another step in the decades-long erasure of the fact that our sophisticated and highly effective immune systems work well and dont need any assistance from the biomedical/pharmaceutical industry. Na enkele dagen van stilte nam Vanden Bossche vandaag zijn camera en reageerde met een video op hetgeen in de media is verschenen. En nooit is het probleem daardoor groter gemaakt. This is why in case of bacterial disease it is critical to not only chose the right type of antibiotic (based on the results from an antibiogram) but to also take the antibiotic for long enough (according to the prescription). Geert Vanden Bossche is een Belgische dierenarts, viroloog, zelfverklaard mRNA-vaccinatie specialist en onafhankelijk onderzoeker en adviseur op het gebied van vaccins. He is no stranger to vaccines. Er is dus nog zeer veel onderzoek nodig naar NK-cellen. In any case, for someone who is so not antivaccine, Dr. Vanden Bossche sure is good at providing ammunition to the antivaccine movement. Geert Vandenbossche, Patric Van Oostveldt (UGent) , Jo Demeester (UGent) and Jean Paul Remon (UGent) ( 1993 ) BIOTECHNOLOGY AND BIOENGINEERING. Specifically, Im referring to the abuse of evolutionary theory by antivaxxers to claim that vaccines select for more deadly variants of pathogenic viruses and bacteria, making mass vaccination programs dangerous or even potentially catastrophic. In deze video legt vaccinoloog Corinne Vandermeulen uit waarom er een groot verschil is tussen antibiotica en vaccins (lees eronder voort): Het klopt ook niet dat een onvolledige vaccinatie tot meer nieuwe vormen van het virus zou leiden. As I suspected, Dr. Vanden Bossche is selling something. Unless I am scientifically proven wrong, it is difficult to understand how current human interventions will prevent circulating variants from turning into a wild monster. "Vanden Bossche received his DVM from the University of Ghent, Belgium, and his PhD degree in Virology from the University of Hohenheim, Germany. https://nl.wikipedia.org/w/index.php?title=Statisten&oldid=63222793, Wikipedia:Pagina's die ISBN magische links gebruiken, Creative Commons Naamsvermelding/Gelijk delen. When this happens, the immune system has to rely on more specialized effectors of our immune system (i.e., antigen-specific Abs and T cells) to fight the pathogen. Geert Vanden Bossche is a scientist who published an open letter warning of global catastrophe due to deadly variants of COVID-19 selected for by mass vaccination. Dr. Geert Vanden Bossche, is a world-class certified expert in microbiology and infectious disease, who also has a Ph.D. in virology and a longstanding career in human vaccinology. As NK cell-based immune defense provides sterilizing immunity and allows for broad spectrum and fast protection, it is reasonable to assume that harnessing our innate immune cells is going to be the only type of human intervention left to halt the dangerous spread of highly infectious Covid-19 variants. Reading the letter, what it reminded me, more than anything else, is an article that Andrew Wakefield wrote about the MMR vaccine and measles, published a few months before the pandemic hit. Thus if evidence emerges that particular variants do appear to influence vaccine efficacy, it should be possible to periodically reformulate the vaccines so that they better match the circulating strains. And so am I. I searched PubMed for what I expected to be an extensive publication record on vaccines and foundeight publications, the most recent of which was from 1994 and none of which have anything to do with vaccines. Not for him is the too-slow process of seeking feedback from fellow experts or publishing in the scientific literature (even on a pre-print server). Ten derde wijst hij erop dat de gezondheidsrisico's van Covid-19 voor gezonde kinderen, zoals ziekenhuisopname, verwaarloosbaar klein zijn en dat vaccinatie vanuit dat oogpunt voor die groep geen enkele zin heeft. | Voice for Science and. 10.8K. This new type of vaccines harnesses the power of the immune system by unlocking the untapped potential of self-centered Natural Killer (NK) cells capable of recognising these unconventional antigens. It has been observed that over time Mareks disease virus has become more virulent, and this has been attributed classically to a leaky vaccine effect. There you have it, the lone scientific maverick who is the only one willing to speak out about against a horror being perpetrated by conventional medicine and science that they dont want you to know about or discuss, a horror thats so urgent that he must speak now. Snoeck noemt het onomwonden technische nonsens die voor een niet-wetenschapper moeilijk te doorprikken zijn. De experten zitten op twitter fact-checkers te liken en roepen mij op aan de juiste kant te staan. A very similar mechanism may also apply to viruses, especially to viruses that can easily and rapidly mutate (which is, for example, the case with Coronaviruses); when the pressure exerted by the armys (read: populations) immune defense starts to threaten viral replication and transmission, the virus will take on another coat so that it can no longer be easily recognized and, therefore, attacked by the host immune system. This growing threat has led what many senior public health officials in the UK and the U.S. to describe as the post-antibiotic apocalypse and the end of modern medicine. It is estimated that 50,000 annual deaths occur in Europe and the U.S. from infections that antibiotics have lost the power to treat. So in fewer than 80 years, we have reached the point at which, for example, with prosthetic surgery, wards are being closed down, patients are being sent home, and operations are no longer possible, because once the prosthesis becomes infected with such bacteria, it is virtually impossible to get rid of them. Vanden Bossche presented his ideas to the public in a series of open letters or powerpoint presentations on his personal website. Dat is volgens de officile data enkel het geval in Chili. Perhaps no more tired a trope exists in the world of faux cures than the "I have found a problem that no other scientist in the world has thought of and only my untested and unproven cure can stop it" gambit. Claims that Belgium has the best fries in the world! Is het Russisch volk goedgelovig en volgzaam? Geert Vanden Bossche, PhD, DVM Independent Researcher --- Mar 2018 - Present Managing Director VARECO Sep 2012 - 2019 Europe Independent vaccine consultant with a long- standing track record in Academia, Vaccine Industry and Global Health (GH); providing support on vaccine project management as Knack wou mijn reactie niet publiceren, het was nochtans een eer-rovend vuilbakartikel van Rien Emmery. Kunnen complimenten de wereld verbeteren? Hij wordt op YouTube voorgesteld als een wereldwijde vaccinautoriteit met een grote reputatie, maar dat klopt niet. Dat zal volgens hem wereldwijd tot veel doden leiden. My statements are based on nothing else but science. "The underlying fallacy," Omer explained, is that a natural infection is better than a vaccine. Experts and politicians have remained silent while obviously still eager to talk about relaxing infection prevention rules and springtime freedom. Vanden Bossche asserts that COVID-19 vaccines pose a unique risk of producing dangerous variants in part because people who are vaccinated will be spreading the mutations while asymptomatic. In deze video verwijst vaccinoloog Isabel Leroux-Roels naar de Spaanse griep, die ook minder dodelijk werd (lees eronder voort): Vanden Bossche zegt dat hij een alternatief heeft voor de huidige coronavaccins: een NK-vaccin, gebaseerd op zogenoemde natural killer-cells. The classic example of a leaky vaccine is actually the one for Mareks disease, caused by a herpesvirus that infects chicken and causes lymphoma among other illnesses. 1499-1505), Flemish painter. Before I get to Vanden Bossches open letter and his warning to the world that mass vaccination with the current COVID-19 vaccines is likely to lead to a global catastrophe due to the proliferation of ever-more-transmissible COVID-19 variants (as if the COVID-19 pandemic itself hasnt been a global catastrophe! Selecting targeted mutations in the S protein is, therefore, the way to go in order for the virus to enhance its infectiousness in candidates that are prone to geting [sic] the disease because of a transient weakness of their innate immune defense. Hij werkte in zijn carrire ook aan vaccins, maar publiceerde daar zeer weinig over en bleef nooit lang aan het werk in de sector. De tekst is beschikbaar onder de licentie. In general, you would have a hard time identifying any human vaccine that could be called leaky (though emerging findings regarding influenza vaccines give hints that there may be a leaky vaccine effect involved, given their excellent efficacy among children, who are critical vectors, I am not so convinced- though if we do grant that they are leaky, this only serves to undermine Bossches argument). Hij was daarbij kritisch over de veiligheid van een ebolavaccin. As a scientist I do not usually appeal to any platform of this kind to make a stand on vaccine-related topics. Bij de vorming van de Verenigde Nederlandse Staten in 1789 vormden zij de eerder conservatieve fractie tegenover de vonckisten. Hes also conflating innate immune responses with specific immune responses induced by either infection or vaccination. National Center for Complementary and Integrative Health, Steven P. Novella, MD Founder and Executive Editor, David H. Gorski, MD, PhD Managing Editor, allowing infection and natural herd immunity to occur is better, American Association of Physicians and Surgeons, The Sixth Extinction: Vaccine Immunity and Measles Mutants in a Virgin Soil, excellent rebuttal of Dr. Vanden Bossches mangling of immunology, proofreading mechanism that results in a low mutation rate, Andrew Wakefield wrote about MMR and vaccines, Nirenbergs demolition of Dr. Vanden Bossches nonsense, The Not-So-Hidden Agenda Behind Bossches Concern Over COVID Mass Vaccination, surgical oncologist at the Barbara Ann Karmanos Cancer Institute, American College of Surgeons Committee on Cancer Liaison Physician, Ear Acupuncture for Procedural Pain in Neonates: More Randomized Controlled Nonsense. In an effort to sidestep this self-evident solution, Vanden Bossche seems to have made up a second mechanism to stoke fear over COVID-19 vaccines. ", The notion that lockdowns have weakened our innate immune system is equally without basis. Menu. "The food you eat isnt sterile, he explained, the dust you inhale isnt sterile, the water you drink isnt sterile.. We hebben Geert Vanden Bossche gevraagd om te reageren, maar hij verkoos dat niet te doen. This material may not be reproduced without permission. Dr Vanden Bossche also coordinated the Ebola vaccine Even so, concern about immune escape is one reason why Pfizer, BioNTech, and Moderna used the entire SARS-CoV-2 spike protein, rather than specific segments of it that might serve as antigens, so that the polyclonal antibody immune response generated would be broad and unlikely to be escaped with single mutationsor even multiple mutations. Dr. Vanden Bossche has also taken to social media to air his concerns, and his message has been enthusiastically embraced by antivaxxers: Lets just say this. Aangezien het geen debat betreft maar een reactie op een reactie in de vorm van een monoloog is het als leek moeilijk in te schatten wie er wetenschappelijk gelijk heeft. Bioavailability of two ibuprofen oral paste formulations is fasted and non fasted ponies. Duitsland blokkeert goedkeuring, Auto rijdt binnen in huis in Mol, bestuurder pleegt vluchtmisdrijf. However, NK cell-based vaccines will primarily enable our natural immunity to be better prepared (memory!) Variants are "a thing to keep an eye on," Saad Omer, an epidemiologist who serves as director of the Yale Institute for Global Health, told us in a phone interview. Zijn pleidooi werd vooral opgevangen en verspreid in de vaccin-kritische beweging. Is Vanden Bossche fout met zijn theorie of is hij een kiezel in de schoen van de media en experten die het debat domineren omtrent de covid aanpak. Het werkt op verschillende fronten tegelijk. In deze video legt immunoloog Herman Favoreel uit hoe NK-cellen werken (lees eronder voort): Hoever staat de wereld nu in het onderzoek naar NK-vaccins? So its not surprising that Dr. Vanden Bossches letter reminds me of Andrew Wakefields warning about the MMR vaccine. This is a very confused argument. Come to think of it, the similarities between Dr. Vanden Bossche and Andrew Wakefield strike me as stronger than ever now, given that, as well documented by Brian Deer, Wakefield basically published his fraudulent science to support the claim that the MMR vaccine causes autism in order to make a market for his own single vaccine against the measles. Nog meer mensen laten sterven?. "It is," Vanden Bossche asserted in one of his letters, "reasonable to assume that vaccination of young and healthy people will inevitably lead to long-lived suppression of their variant-nonspecific, innate immune defense." However, even if this phenomenon occurs with a human vaccineit doesnt, as far as we knowthats an even more compelling reason to be vaccinated. Moreover, as Nirenberg points out, there is an increasing body of evidence that the COVID-19 vaccine is not leaky. One such claim that I hadnt yet seen is another favorite antivax claim, although admittedly its a rather niche claim in that you dont hear it too often. Author of 'From Midnight to Moonlight' - a book about cats and angels. Er bestaat geen bewijs dat de beweringen van Geert Vanden Bossche kan ondersteunen. Hoe schandalig is het brugpensioen van Marc Leemans? Voorlopig dus nog even koffiedik kijken en vooral genieten van de lente. Clearly, variability in the spike glycoprotein can affect the efficiency of antibody neutralisation. Samen zetten zij zich evenwel af tegen het beleid van keizer Jozef II en streefden zij naar de onafhankelijkheid van de Zuidelijke Nederlanden, hetgeen leidde tot de Brabantse Omwenteling (1789 - 1790). De inhoud is, tenzij anders aangegeven, beschikbaar onder. As the innate immune system cannot remember the pathogens it encountered (innate immunity has no so-called immunological memory), we can only continue to rely on it provided we keep it trained well enough. Indien hij gelijk krijgt natuurlijk. As the unprecedented extent of human intervention in the Covid-19- pandemic is now at risk of resulting in a global catastrophe without equal, this call cannot sound loudly and strongly enough. p.528-531. I will note that it is truly astounding how many statements that a supposed expert in immunology and vaccines can make that are just plain out-and-out wrong. Deze pagina is voor het laatst bewerkt op 2 nov 2022 om 05:23. Enjoy! Antibiotica werken rechtstreeks in op de bacterie. De geschiedenis toont echter aan dat het helemaal niet gevaarlijk is om massaal te vaccineren tijdens een epidemie. Dr. Vanden Bossche is using an eerily similar argument about COVID-19 vaccines and SARS-CoV-2, the coronavirus that causes COVID-19, to the one used by Wakefield about MMR vaccine and measles. The role of spike protein variability inT cell immunity is likely to be elucidated in experimental studies in the next few months; a priori, the enhanced repertoire of T cell epitopes makes the loss of cytotoxic activity or recognition improbable. Movies. Hij pleit daartegen, in de eerste plaats omdat deze vaccins volgens hem de natuurlijke immuniteit, die bescherming biedt tegen een veel breder spectrum van pathogenen dan het vaccin, kan verdringen. Freya Van den Bossche (born 26 March 1975) is a Belgian ( Flemish) politician and daughter of prominent former Belgian politician Luc Van den Bossche. As those have stronger affinity for the pathogen (e.g., virus) and can reach high concentrations, they can quite easily outcompete our natural Abs for binding to the pathogen/virus. Hij waarschuwt met name voor de risico's van het vaccineren van kinderen met mRNA-vaccins. ), vertelde Vanden Bossche tijdens een congres in Ohio begin deze maand. So it is scientifically based but the conclusions of the chapters are accessible to laymen as is the entire chapter "Answers to Key Questions" Er is al vaak gevaccineerd tijdens een epidemie, en dat heeft nog nooit tot grote sterfte geleid. 53(4) . Covid-19 vaccine mandates for children: what is the science behind this? Dat zal volgens hem wereldwijd tot veel doden leiden. Maar met iets experimenteels als NK-vaccins zijn we snel vijf jaar verder. I noted then that there was no evidence that mass vaccination with MMR had produced variants of the measles vaccine resistant to the immunity produced by the vaccine, just as I note now that there is as yet no evidence that SARS-CoV-2 variants are resistant to the immunity produced by current COVID-19 vaccines. Mass vaccination programs, he claims, are "turning vaccinees into asymptomatic carriers" who can unknowingly spread these more dangerous strains by "shedding infectious variants." Dit toont nogmaals de nood van open debat aan. Your membership is the foundation of our sustainability and resilience. Why? RNA viruses like SARS-CoV-2 do mutate. After all, if a human vaccine lets deadlier versions of a disease flourish, that is all the more reason to be protected from those deadly strains. See the complete profile on LinkedIn and discover geert . Such claims are generally an offshoot of another favorite antivaccine claim, namely that the diseases being vaccinated against are so innocuous that vaccinating against them is overkill and allowing infection and natural herd immunity to occur is better, a trope that has also been resurrected about COVID-19, a disease thats killed well north of 500K people in just the US in a little over a year. [1] Zijn proefschrift gaat over veranderingen in oppervlakte-eigenschappen van virale deeltjes en hun infectieus gedrag. Ik zie niet hoe ook maar iets van deze theorie kan kloppen., Leroux-Roels stipt ook nog aan dat Vanden Bossche geen bewijzen aandraagt om die claim te onderbouwen. Failure to comply with these requirements is at risk of granting microbes a chance to survive and hence, may cause the disease to fare [sic] up. Because his proposed solution appears to be a fantasy, its effect would be to stop vaccinations completely and replace them with nothing. De Vlaamse veearts Geert Vanden Bossche pleit ervoor om alle coronavaccinaties stop te zetten. Geert Vanden Bossche is een Belgische dierenarts[1], viroloog[1], zelfverklaard mRNA-vaccinatie specialist en onafhankelijk onderzoeker en adviseur op het gebied van vaccins. Therefore he has zero credibility when it comes to advising the public or anyone else about how to avoid negative effects of mass vaccination. He held adjunct faculty appointments at universities in Belgium and Germany. En wat met die massale sterftegolf die Geert Vanden Bossche voorspelt? Vanden Bossche studeerde achtereenvolgens aan de Universiteit van Namen en Gent, waar hij in 1983 zijn doctoraalexamen diergeneeskunde (DVM) haalde (cum laude). Van den Bosch is a Dutch toponymic surname, originally indicating either an association with a forest ("bosch", modern Dutch "bos"), with a place/dwelling named "Den Bosch" or with the city Den Bosch.In the Netherlands about 10,200 carried the name in 2007, while in Belgium 3,755 people were named Van Den Bosch and another 3,164 were named Vandenbosch, Vandebosch or Vanden Bosch in 2008. This will, indeed, require large vaccination campaigns. https://t.co/DPYKE7kxmM, Geert Vanden Bossche (@GVDBossche) March 15, 2021, The science behind the catastrophic consequences of thoughtless human intervention in the Covid-19 pandemic. 455 () [US] 2021/06/16() 09:32:54. Mass vaccination will only work if the vaccine prevents or decreases transmission; i.e., if it is not leaky (although he doesnt use the term). Al bij n dosis zal de kans op mutaties verminderen, omdat iemand ook na n dosis van het vaccin al minder besmettelijk wordt. Geert Vanden Bossche is a scientist who published an open letter warning of global catastrophe due to deadly variants of COVID-19 selected for by mass vaccination. Vervolgens wijst hij erop dat de gekende experten nooit ge-fact-checkt worden. Maar een vaccin werkt niet rechtstreeks in op een virus." Mensen die gevaccineerd zijn, voelen zich soms een dag niet goed, met koorts bijvoorbeeld. Again, the possibility that COVID-19 might be developing resistance to vaccines or immune escape is not a reason to halt the vaccination campaign. A recent review article suggests that immune escape by variants of SARS-CoV-2 is a possibility, but one that hasnt been definitively observed or demonstrated yet: So is there cause for concern? And Dr. Vanden Bossches concerns are based on Science! Unfortunately, it remains untouched by those who have the power to act. De serie gaat over Caro en haar vrienden in hun avonturen in een middelbare school: het SAS (de fictieve School Aan Stroom). NK cells have increasingly been described to be endowed with the capacity to acquire immunological memory. The resulting type of immune response is unprecedented and licenses the host immune system to readily eliminate infection or to cure disease across a broad range of unrelated pathogens and/ or mammalian species.

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