Also tell them about any vitamins, herbs, and supplements you use. However, consuming large amounts of alcohol can actually cause anemia in some people. People with IDA have low blood levels of hemoglobin. endobj You may report side effects to FDA at 1-800-FDA-1088. Many patients with kidney disease cannot get enough iron from food and require injections. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Dizziness. Last updated August 20, 2020. Injectafer and Feraheme are both brand-name drugs. Its given by either intravenous (IV) infusion or slow IV injection. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Injectafer is approved to treat iron deficiency anemia (IDA). It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Someside effectsare temporary or last as long as the person continues takingprescription medicine. (Hemoglobin is a protein thats found inside your red blood cells.). Upset stomach or throwing up. Cardiovascular health: Insomnia linked to greater risk of heart attack. Side effectswill last a very long time if the cause of them is not resolved. Here we look at how Injectafer and Venofer are alike and different. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Severeside effectsmay end up causing a lot of disruption in a persons life. You may report side effects to FDA at 1-800-FDA-1088. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. You can also write a reminder on your calendar. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Is the ketogenic diet right for autoimmune conditions? Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. These changes could help improve your anemia on a long-term basis. <> But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. This test measures the amount of hemoglobin in your blood. Side effectsare uncomfortable reactions to medications or drugs. You will need to talk about the benefits and risks to you and the baby. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Injectafer and Venofer can cause very similar side effects, but some different ones as well. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Following an LSD trip, users may experience a sort of 'comedown.'. Venofer is for use in adults and children at least 2 years old. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. What are the side effects of Venofer? Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. So you wont pick up this medication from a pharmacy. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Blood tests may be needed to check for unwanted effects. Joint pain. Most people do not know how long theirside effectswill last until they go through them. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. You may report side effects to Health Canada at 1-866-234-2345. ByDr. This means you would get two Injectafer doses of 720 mg each. And these two doses need to be separated by at least 7 days. Version: 7.01. Call your doctor for instructions if you miss an appointment for your Venofer injection. For example: Say you weigh 105 pounds (about 48 kilograms). Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. Pain, swelling, or redness at the injection site may occur. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. . Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. With slow IV injection, the drug is given as a single, slow injection into your vein. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. So we cant say for sure whether the drug is safe to use while youre pregnant. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Do not share your drugs with others and do not take anyone else's drugs. I hope you found answers and are feeling better now. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Injectafer is available only as a brand-name medication. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Examples of these side effects include dizziness and nausea. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Why is the range so wide? stream Theyll likely have you stop taking the pills while youre using Injectafer. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. Talk with the doctor. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Then your body uses that iron to make hemoglobin and RBCs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. With this condition, you also have a low hemoglobin level. <> Discuss the risks and benefits with your doctor. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Serious side effects from Injectafer arent common, but they can occur. Have blood work checked as you have been told by the doctor. In the second group, some people switched from taking iron by mouth to taking Injectafer. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. IQVIA [NSP Audit from MAT November 2013 to November 2018]. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. Pain, swelling, or redness at the injection site may occur. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). But you kidneys need iron in order to make EPO. Mental healthdisorders like depression may requireantidepressantsto treat. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . The drug helps increase your hemoglobin level back to a value thats within the normal range. Talk to your pharmacist for more details. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. There are different types of anemia, but IDA is the most common type. Your doctor will be able to see how Venofer is working by reviewing your blood tests. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. All rights reserved. Brand-name medications usually cost more than generics. Some people only need one treatment course of Injectafer. If youre interested in finding an alternative to Injectafer, talk with your doctor. Dizziness. Iron infusion side effects vary depending on which form is being used. Orofer S 50 Injection 1 Injection in 1 Packet 147. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. (A generic drug is an exact copy of the active drug in a brand-name medication.). Pain in your limbs. If your symptoms or health problems do not get better or if they become worse, call your doctor. Yes, in some cases it may. Injectafer contains the active drug ferric carboxymaltose. treatment schedule in further detail. This can be very helpful in . If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. A lack of iron can lead to iron deficiency anaemia if left untreated. (IV iron is absorbed by the body more rapidly than oral iron.) These are not all of the side effects that may occur. If you have diarrhea while youre taking Injectafer, call your doctor. They have been a god send. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. These nutrients include iron, vitamin B12, and folate. I had my first infusion of 1gm 10 days ago. Heart failure: Could a low sodium diet sometimes do more harm than good? Do not double the dose to catch up. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Injectafer helps to treat IDA by providing an iron infusion directly into your body. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Injectafer infusions are given over a period of at least 15 minutes. Be ready to tell or show what was taken, how much, and when it happened. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. This includes your doctors, nurses, pharmacists, and dentists. Should I avoid certain foods while taking Venofer Vial? Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Do not start, stop, or change the dose of any drug without checking with your doctor. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. In the US - Call your doctor for medical advice about side effects. generalized weakness. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. How is Venofer (iron sucrose) given? The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Call your doctor for medical advice about side effects. These side effects can range from being mild to severe. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. fever. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. No, you most likely wont take Injectafer long term. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. The infusion will take between 15-30 minutes if it is given in. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. WebMD does not provide medical advice, diagnosis or treatment. This medicine may cause serious types . Check with your pharmacist if you have questions about the best way to throw out drugs. I was surprised too but the Dr said it definitely sounds like a reaction. Follow your doctor's directions carefully. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Keep all regular medical and laboratory appointments. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Things to remember when you fill your prescription. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. It's a more immediate treatment than supplements or dietary changes. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. %PDF-1.3 No, you wont need to take iron pills while youre using Injectafer. Your doctor will do laboratory tests to monitor your response. Generics tend to cost less than brand-name drugs. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Keep all drugs in a safe place. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). The drug helps increase your hemoglobin level back to a value thats within the normal range. Copyright 1996-2023 Cerner Multum, Inc. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). Remember that it is best to get your vitamins and minerals from food whenever possible. Do not exceed 1,500 mg of iron per dosing course. Your doctor will determine the best dosage to fit your needs. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. During pregnancy, this medication should be used only when clearly needed. However, diarrhea it isnt very common in people using Injectafer. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. But you likely wont feel the drug working inside of you. Headache. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. With anemia, you have a low level of red blood cells (RBCs) in your body. This medication is given by injection into a vein as directed by your doctor. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. (A generic drug is an exact copy of the active drug in a brand-name medication.) Some drugs may have another patient information leaflet. If you notice any changes to your normal blood pressure, call your doctor right away. (Hemoglobin is a protein thats found in red blood cells.). In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. taste impairment. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Nausea. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. For additional information, contact your healthcare provider. It depends. pain in the arms or legs. Brand-name medications usually cost more than generics. Source: Wolters Kluwer Health. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. This medication passes into breast milk. administered at your doctors office or an infusion center. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Venofer is given as an infusion into a vein. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. 2 0 obj You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. An iron infusion is a way to increase the body's iron levels quickly. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Sharing this information can help you avoid potential interactions. But for other people, their IDA returns after treatment with Injectafer. Nose or throat irritation. Ask your doctor or healthcare provider if Venofer is the right choice for you. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. Best food forward: Are algae the future of sustainable nutrition? Here's some detail on certain side effects this drug may cause. Precautions. If you think there has been an overdose, call your poison control center or get medical care right away. * This is a partial list of mild side effects from Injectafer. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Tell all of your health care providers that you take Venofer. We comply with the HONcode standard for trustworthy health information. They can give you tips on how to deal with any side effects that may be bothersome. I actually was constipated after my 3rd but didn't think anything of it. <> Cancer patients who have anemia and are taking an ESA. As with all medications, the cost of Injectafer can vary. <> In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. Theseside effectscan range from being mild tosevere. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). After the infusion, you can drive yourself home and return to your usual activities. Instead, youll start by receiving just one treatment course of Injectafer. Can diet help improve depression symptoms? Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use.

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